Last Updated: Dec 2, 2020
SteroidCycle.org is intended for informational purposes only and does not take the place of professional medical advice.

Sustanon 250 is a powerful testosterone steroid made up of a four different esters of testosterone combined into the one solution.

One testosterone ester alone is a powerful compound to take for bodybuilding, but the combination of four allows you to reap the benefits of the way each ester is consumed by the body with a mix of both fast acting and longer lasting esters all being administered in the one dosage.

There are many reasons for the popularity of Sustanon:

  • 4 esters in one
  • Provides a combination of fast and slow acting esters
  • Gives a fast release of testosterone within first 24-48 hours
  • Useful for bulking and strength cycles, as well as cutting

My Sustanon 250 cycle guide has been broken down into the following sections:

What is Sustanon 250?

Sustanon 250 is the brand name of this injectable form of testosterone steroid. It has a medical use of treating men who have low levels of natural testosterone by acting as a testosterone replacement therapy.

There are 4 testosterone esters in Sustanon 250. An ester is an extra chemical addition added to the regular testosterone hormone which is then released in the body after injection. The timing and rate of release of each ester is what makes the four of these different: the testosterone itself is exactly the same on each ester.

The four testosterone esters used in Sustanon 250 are:

Testosterone Propionate (30mg)

Test Prop is a fast acting ester with a short half life of around two or three days. This ester gets Sustanon working quickly to raise blood testosterone levels after administering your injection.

It ensures that Sustanon is able to get your testosterone levels raised within just 24 to 48 hours of your injection, providing the initial boost at the start while the other esters in Sustanon take their time to release over the next two to three weeks.

Testosterone Propionate injections when taken alone would need to be administered everyday, so by making use of this ester in Sustanon you get the full benefit of Testosterone Propionate’s quick acting effects without having to worry about daily injections.

Testosterone Phenylpropionate (60mg)

Test Phenylpropionate a relatively fast acting ester but one that can take anywhere from one to three weeks to fully release into the body ensuring it helps maintain a steady supply of testosterone as part of the Sustanon formula.

Testosterone Isocaproate (60mg)

Testosterone Isocaproate is also medium acting ester with a half life of about 4 days. This is an ester that is not available as an individual product but only consumed in formulas like Sustanon and other mixed testosterone ester preparations.

Testosterone Decanoate (100mg)

Test Decanoate is a slow acting and long lasting ester that keeps the effects of Sustanon active long after the injection. It has a long half life of over 20 days.

Just like Isocaproate, Testosterone Decanoate is generally not found as a single testosterone ester and instead only included in mixed ester solutions like Sustanon, making this one of the very few ways you can take advantage of the long lasting benefits of the Testosterone Decanoate ester.

The 250 portion of the name comes from the ratio of the combined four esters that are blended to make up 250mg of testosterone, including some esters that are available as single ester products and others that are only available in Sustanon itself.

The goal of Sustanon through the use of these four esters is to provide the dual benefit of having a very quick release of the hormone so peak levels are obtained and then these levels are maintained through the ongoing release of testosterone with the varying esters.

This means your testosterone levels don’t dip or start leveling off quickly like they can when using something like testosterone propionate on its own, which would require much more frequent injections.

This makes Sustanon 250 purely a testosterone compound and one what has had no alterations at all to the original testosterone hormone. Testosterone, as the natural male sex hormone, has an anabolic rating of 100 and an androgenic rating of 100 – Sustanon 250 is pure testosterone. Other types of steroids skew these ratings one way or the other based on making modifications to testosterone or similar hormones.

So while Sustanon 250 as pure testosterone comes with many substantial benefits, it also comes with some potentially serious side effects which we need to be aware of, and learn how to combat them during a testosterone cycle as well as developing a post cycle therapy plan to recover afterwards.

Editor’s Note: For real, NO-BS information on cycling steroids be sure to check out Straight From the Underground (my recommended underground steroid handbook). Everything in this book is based on first hand experience, not theory.

Sustanon 250 Benefits

After injecting Sustanon 250, total plasma testosterone levels will start to increase and you will reach the peak level of total testosterone at anywhere between the 24 to 48 hour mark after the injection. The main benefits of Sustanon are:

Boosts Protein Synthesis

Boosts protein synthesis resulting in a faster protein building process in the cells and as the building blocks of muscle, this means muscle repairs and grows faster.

Boosts Nitrogen Retention

Nitrogen retention is boosted by Sustanon. The muscle tissue contains a large amount of nitrogen and some of this is lost during intensive exercise.

By retaining as much nitrogen in the muscle tissue as possible, the body can remain in a more anabolic state for muscle growth while minimizing or removing the risk of muscle loss.

Nitrogen is also a critical component of amino acids which are what build protein. When more nitrogen is inputted or retained in the body compared the amount of nitrogen lost, the total available protein also increases.

Increases the Production and Release of Insulin-Like Growth Factor-1 (IGF-1)

Insulin-Like Growth Factor-1 (IGF-1) is important for the functioning of all cells. It facilitates protein synthesis and regulates the storage of fat so it can be efficiently used for energy production. IGF-1 positively impacts metabolism and helps with the increase of lean body mass and the loss of body fat.

IGF-1 is also important for bone health, nerve tissue regeneration and ligament strength. We can see how powerful IGF-1 alone is, but this is just one small aspect of the benefits that Sustanon 250 can provide as a pure source of testosterone.

Improves Athletic Performance

Performance enhancement is another reason people choose to use Sustanon. Improving athletic performance is to be expected when your testosterone levels are increased and optimized. This results in much better muscle endurance, taking your workouts to a new level. Noticeable improvements in recovery can also be expected as the full effects of testosterone kick in.

Sustanon 250 has great benefits for both bulking and cutting goals. This is no surprise when we consider the powerful anabolic effects which are vital for both gaining muscle and for losing fat without the loss of muscle tissue. This gives Sustanon a place in both a bulking cycle and as part of a cutting cycle alongside other fat burning compounds.

Bulking Benefits

While not the most anabolic steroid out there with some others having a much higher anabolic rating, Sustanon can still be used in a steroid cycle where gaining strength and mass is the goal. When using Sustanon as the main bulking agent you can still expect to see quality gains and without the gaining of fat thanks to the way testosterone enhances the metabolic system to more efficiently burn fat.

Cutting Benefits

Using a form of testosterone during a cutting cycle is a popular strategy for anyone aiming to trim down and get ripped with the use of powerful fat loss steroids and one of the most important reasons is because of how Sustanon helps retain lean muscle tissue while you’re shredding fat.

Cutting requires a calorie restricted diet and intense cardiovascular activity which can easily result in a loss of muscle if the body falls into a catabolic state. Sustanon ensures you remain anabolic while cutting so not only do you improve body tone but also burn fat faster by retaining that muscle tissue.

How to Take Sustanon 250?

Thanks to its long lasting effects, Sustanon 250 is injected less frequently compared with using most single testosterone esters. This makes it more appealing for people who aren’t keen on regular injections and also reduces the risk of injury or pain to the areas of muscle where the solution is injected.

You might inject Sustanon for performance enhancing purposes anywhere from once to three times weekly so you’ll need to work out which muscle area works best for you, and ideally rotate the injection site to avoid ongoing irritation and pain. Most people choose to inject in the largest muscles including the deltoid, vastus lateralis (thigh), and gluteal muscles (buttocks).

Sustanon 250 Dosage

Beginner, Intermediate, and Advanced Sustanon 250 Dosage

An effective dose for men using Sustanon 250 can start at 500mg weekly and go up to 2000mg weekly for advanced users. Beginners are always advised to start at the lowest effective dose and for some, this could even go as low as 300mg weekly. When combining it with other compounds, 500mg per week is almost always enough Sustanon to have a positive effect.

Advanced users are known to raise dosage anywhere between 1000mg and 2000mg weekly however this is rarely the case when other compounds are being used and such high doses by advanced users are almost always only done when Sustanon 250 is being used alone. These higher doses will raise your risk of severe side effects substantially.

Female Sustanon 250 Dosage

Sustanon is a very powerful steroid with strong androgenic activity and for that reason it is not recommended that women use this injection because it is certain to bring about the development of masculine traits like a deepened voice and hair growth.

Women who are really wanting to use testosterone for performance enhancement purposes are well advised to look at single esters only rather than the much more powerful 4 ester blend of Sustanon.

Typical Sustanon 250 Cycles

To get the most out of Sustanon a cycle length should be at least 10 weeks because of the slower release rate of one of the esters which allows the effects to be long lasting. A 10 week cycle should be considered a bare minimum however, with 12 to 14 weeks allowing the most benefits thanks to the longer half life of this 4 ester combination.

Beginner Sustanon 250 Cycle

Using Sustanon on its own or with one other compound for bulking is usually the choice of anyone starting out with Sustanon. A popular beginner cycle is to use the powerful bulking kickstart steroid Dianabol for the first 4 weeks with Sustanon also being used during that time, and continuing with Sustanon for another 8 weeks to maintain the gains made with Dianabol.

Intermediate Sustanon 250 Cycle

Intermediate users can add an extra compound to the above cycle and this usually comes in the form of Deca-Durabolin. Dianabol provides the initial kick off for gains at the start of the cycle for four to six weeks, while Sustanon 250 and Deca are taken for the entire 12 week duration of the cycle.

Advanced Sustanon 250 Cycle

Advanced users will often extend a Sustanon cycle out to 16 weeks to reap the full benefits of this long lasting steroid. For an advanced bulking cycle making use of Sustanon, the same other compounds are often used and these Dianabol and Deca, with the difference between beginners and intermediate users being that advanced users will significantly increase the dosage of these other compounds, while still using Sustanon to retain a base testosterone supply over the entire 16 week cycle.

Sustanon 250 Only Cycle

Beginners using Sustanon alone in a cycle can start from 300mg to 500mg weekly with 12 weeks being the minimum length for this cycle, while advanced users will choose to take to three times that dosage during a 12 week cycle.

Alternatively when using Sustanon as base testosterone compound only during cycles that are more focused on other steroids, low doses can be effective below 200mg weekly which are run for as long as your regular steroid cycle is active.

Stacking Sustanon 250

Sustanon is well known for its compatibility for stacking with virtually any other type of anabolic steroid. Common stacks include Deca-Durabolin, Trenbolone and Dianabol particularly in the off season while cutting stacks make use of powerful compounds like Anavar, Winstrol and Trenbolone where Sustanon 250 can provide a base testosterone supply to help retain lean muscle during calorie deficit phases.

What Results Can I Expect Using Sustanon 250?

Your results from Sustanon will depend on several different factors: what you’re using it for (bulking, cutting or testosterone maintenance), any other steroid compounds you’re stacking it with in a cycle, your dosage and cycle length, your workout and diet routines, and how effective your post cycle therapy plan is. Genetics will also play a role.

With these aspects in mind we can see how a one size fits all expectation of certain results does not exist, but it’s possible to gain some idea of what to expect when you use Sustanon 250.

For most guys it will be three or four weeks until you start seeing some noticeable gains, but again this will heavily depend on other steroids you’re using – particularly when using other compounds that have a higher anabolic rating and can help you pack on mass faster.

In these situations you’ll probably find it difficult to attribute any particular result to Sustanon, but it will be helping your overall gains as part of your wider stack and making sure you are maintaining the level of testosterone needed for strength, muscle gain and fat loss.

A Sustanon only cycle focused on gaining mass which runs for 12 weeks can easily yield you gains of 10-20 pounds by the end of the cycle, as long as you can control water retention and retain the gains with good implementation of PCT afterwards. If you don’t control water retention adequately you can easily lose half the weight gained, which indicates how serious that side effect needs to be taken.

Side Effects from Sustanon 250 Cycle

Like all testosterone steroids, Sustanon 250 has strong androgenic effects and is also an aromatizing steroids which means it causes estrogenic side effects as well. This means that the most dreaded side effects that steroid users face are at high risk of occurring when you use Sustanon including water retention and gynecomastia – these affect not only the appearance of your results but also potentially your health.

Learning how to control all of these side effects is an important aspect of using Sustanon. Here are the main side effects to look out for when using Sustanon 250:

Estrogenic Side Effects

Sustanon (testosterone) is an aromatizing steroid which results in testosterone being converted into the female hormone estrogen.

Men require small amounts of estrogen for normal functioning but the aromatizing process often results in a great imbalance between estrogen and testosterone, causing estrogen to rise beyond normal levels and this brings about familiar side effects. These are:

  • Gynecomastia – the growth of excess tissue on the breast area in males. If this issue is allowed to go on for too long it can reach a stage where surgery is your only option to fix it.
  • Water retention and bloating – retaining too much fluid will give you a bloated look and mask some of the muscle gains you’re making, or make it difficult or impossible to achieve a toned and refined look in a cutting cycle.
  • High blood pressure – water retention can cause blood pressure to rise simply because of the additional fluid being circulated that results in blood pressure increasing.

The higher your Sustanon dosage is, the more likely and more severe the estrogen related side effects will be as levels of that hormone rise further.

Androgenic Side Effects

The testosterone hormone has an even rating of anabolic to androgenic effect at 100 and 100 – or an anabolic:androgenic ratio of 1 – so we can expect the androgenic side effects to be as powerful as the anabolic benefits when using Sustanon as it is simply a testosterone combination steroid.

Besides the androgenic activity of testosterone itself, when that hormone is converted in DHT then a further increase in androgenic effects happen with DHT being a very powerful androgen compared with testosterone.

Not everyone will suffer with all or even any of these side effects as they can be heavily determined by your genetics, but it’s wise to be aware of the possibilities of androgen related side effects with Sustanon, including:

  • Oily skin and acne – increased sebum production can result in acne ranging from mild to severe, especially if you were an acne sufferer in your teens.
  • Baldnesshair loss in males or a noticeable receding hairline can occur if you are genetically predisposed to baldness. This can be difficult or impossible to reverse and means you can experience hair loss sometimes several decades earlier than you were already going to thanks to your genetics.
  • Masculine effects in females – being a strong androgen, Sustanon is not recommended for females because of the virilization side effects which are highly likely. These include hair growth, voice deepening, clitoral enlargement, irregularities with menstruation and an overall major imbalance of having far too much testosterone in the female body which normally only has a very small amount.

So what can you do about these side effects? The only way to manage them or try and prevent them completely in the case of estrogenic effects, is to make use of prescription drugs that were mostly developed to treat breast cancer in women either by blocking estrogen receptors or lowering overall estrogen.

Aromatase inhibitors (AI) are commonly used as are SERMs (Selective Estrogen Receptor Modulators). While SERMs are useful for tackling side effects like gyno specifically because of the way they target estrogen receptors in the breast tissue, AIs reduce overall estrogen levels and can therefore address all estrogenic related activity and as such have become the preferred option for combating these side effects.

Cholesterol

Other side effects at the more serious end relate to Sustanon’s effects on cholesterol health. It can bring about a reduction in levels of good cholesterol (HDL), and this can get worse when you are using an aromatase inhibitor drug which is almost always the case. So people with existing cholesterol issues need to strictly monitor levels and maintain a quality diet with omega-3 and other cholesterol friendly foods and implementing good amounts of cardio into your workouts.

Testosterone Suppression

Natural testosterone production is another unavoidable effect of using Sustanon because the body is receiving high amounts of testosterone from the steroid. This has no effect during your cycle, but causes a drop in testosterone once Sustanon wears off at the end of the cycle. Here is where post cycle therapy is critical to trigger natural testosterone production again, without which you would be waiting many months for normal hormonal function to recover – resulting in severe low testosterone effects including loss of the gains you worked so hard for during your cycle.

Sustanon 250 Post Cycle Therapy

Because of the way Sustanon 250 causes your natural testosterone production to become suppressed or stopped altogether, post cycle therapy is needed to get your normal hormone function back on track. Because Sustanon gives the body a constant supply of testosterone, it is triggered into thinking that it no longer needs to product its own.

When you stop using Sustanon and the effects wear off, you are then in a low testosterone state unless you take action to stimulate normal production again. Without this, you will suffer severe low testosterone effects like loss of muscle, fat gain, low mood or depression, loss of libido, lack of energy and many other issues.

The timing of your PCT cycle after using Sustanon will once again also be influenced by any other steroid compounds you’re using. Sustanon’s longer half life overall means your PCT for this specific steroid should be started about three weeks after your last injection, in order to prevent the crash in testosterone levels that will otherwise occur.

SERMs like Clomid combined with hCG (Human chorionic gonadotropin) will work to restore natural testosterone function.

While aromatase inhibitors might be tempting to use during PCT to suppress overall estrogen, their estrogen suppression effect can often be too powerful, having the reverse effect that you need as males still require small amounts of estrogen rather than zero – for this reason, a SERM combined with hCG is the most recommended post cycle therapy choice.

Common Q&A Related to Sustanon 250

What are the side effects of Sustanon 250?

Androgenic and estrogenic side effects can both come about when using Sustanon. These include breast tissue growth, water retention and increased blood pressure as a result of rising estrogen levels, and androgenic effects like acne and hair loss on the head. The more Sustanon you use, the higher your risk is going to be of experiencing these side effects and the more severe they can become.

How long does testosterone Sustanon stay in your system?

Sustanon’s big appeal is that it contains 4 testosterone esters that makes it simple to get both a fast acting benefit in the early stages while the effects are long lasting thanks to the different release rates and half lives of each ester. It’s possible to have raised testosterone levels up to three weeks after your last Sustanon injection.

How often should I inject Sustanon?

This depends on what your purpose is for using it – whether it is for testosterone replacement or maintenance, or as a performance enhancing compound – and if you are mainly focusing on cutting or bulking.

For testosterone replacement a three weekly injection is often sufficient, while for performance enhancement your dosage and other steroids being used will determine how often you choose to inject. For example if taking Dianabol, a powerful anabolic steroid, a once weekly Sustanon injection is often enough.

Is Sustanon a steroid?

Yes, Sustanon is a blend of 4 testosterone steroid esters so this makes it more powerful than just a single testosterone steroid. Sustanon therefore is like taking four steroids at once but without the need for multiple injections everyday because they are all contained in the one solution.

How do you inject Sustanon?

Sustanon 250 only requires an injection once every week or so depending on your dosage and purpose for using it. Sustanon is an intramuscular injection where the solution needs to go deep into the muscle and the best sites for this are the buttock, upper leg or upper arm.

Even though injections are not too frequent with Sustanon, it can still be a painful injection for some people and this particularly because of the propionate ester which is known to cause some pain, irritation or stinging at the injection site because of its short ester chain.

Can you stack Sustanon with Equipoise?

Yes, Sustanon can be stacked with Equipoise (Boldenone Undecylenate) and this is often done in a cutting cycle but can also be used for bulking as Equipoise is known as a versatile steroid and by combining it with Sustanon you lay a base foundation for testosterone supply throughout your cycle.

When using Equipoise with Sustanon, the Equipoise dosage is usually around the 600mg per week mark for most people with your Sustanon dosage dependent on what you’re trying to achieve with the cycle.

What is the shelf life of Sustanon 250?

The product has a shelf life of 36 months (3 years) when stored correctly. The product should not be put in a fridge or freezer and should be stored below 86 degrees Fahrenheit or 30 degrees Celsius. Low quality Sustanon may spoil sooner and this is yet another reason why you should always seek out a top quality product even if it costs more.

Where can I buy Sustanon?

Like most other steroids, most people buy Sustanon either from a local supplier or on the blackmarket. Prices will vary greatly on where you can source it from and the quality or grading of the product, keeping in mind that Sustanon is illegal in most countries. Compared with many other steroids, Sustanon is on the lower end of the price range.

My Conclusion and Recommendation

Sustanon 250 is a group of both slow and fast acting esters with varying half lives, providing the benefits of all four in the one injection.

Sustanon acts like other testosterone steroids and that makes it useful for contributing to muscle building, fat loss, energy and strength by providing critical testosterone support during a steroid cycle that will usually also include other compounds. Sustanon can be used at low doses to maintain a base level of testosterone or at higher doses for performance enhancement.

If you'd like more real, NO-BS information on using steroids be sure to check out Straight From the Underground (my recommended underground steroid guide). Everything in this book is a real-life experience, not theory.